TXN2 anticorps (AA 101-166)

N° du produit ABIN705971

Détail du produit anti-TXN2 anticorps

Antigène: TXN2 (Thioredoxin 2 (TXN2))

Épitope: AA 101-166

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TXN2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Thioredoxin 2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TXN2

Antigène: TXN2 (Thioredoxin 2 (TXN2))

Autre désignation: Thioredoxin 2 (TXN2 Produits)

Synonymes: anticorps MT-TRX, anticorps MTRX, anticorps TRX2, anticorps 31884, anticorps CG31884, anticorps CG3864, anticorps DTrx-2, anticorps DmTrx-2, anticorps DmelTrx-2, anticorps Dmel\\CG31884, anticorps Trx, anticorps anon-WO0118547.188, anticorps dmtrx-2, anticorps 2510006J11Rik, anticorps AI788873, anticorps Trx2, anticorps zgc:77127, anticorps thioredoxin 2, anticorps thioredoxin-2, anticorps thiol reductase thioredoxin, anticorps thioredoxin 2 L homeolog, anticorps TXN2, anticorps Trx-2, anticorps LOC409451, anticorps VPA0972, anticorps VS_RS18125, anticorps VCD_000568, anticorps VEA_000083, anticorps trx2, anticorps Txn2, anticorps txn2, anticorps txn2.L

Sujet:

Synonyms: mitochondrial thioredoxin, MT-TRX, MTRX, thioredoxin 2 precursor, Thioredoxin mitochondrial, Thioredoxin2, TRX 2, TRX2, TXN 2, TXN2.

Background: Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

ID gène: 25828

Pathways: Cell RedoxHomeostasis