DDX4 anticorps (C-Term)

N° du produit ABIN7091031

Détail du produit anti-DDX4 anticorps

Antigène: DDX4 (DEAD Box Protein 4 (DDX4))

Épitope: C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DDX4 C-term

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DDX4

Antigène: DDX4 (DEAD Box Protein 4 (DDX4))

Autre désignation: DDX4 (DDX4 Produits)

Synonymes: anticorps VASA, anticorps AV206478, anticorps Mvh, anticorps RVLG, anticorps vasa, anticorps vlg1, anticorps DEAD-box helicase 4, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 4, anticorps DEAD-box helicase 4 L homeolog, anticorps DDX4, anticorps Ddx4, anticorps ddx4.L

Sujet:

Synonyms: DDX 4, DEAD (Asp Glu Ala Asp) box polypeptide 4, Dead box protein 4, Dead-box protein 4, MGC111074, MVH, Probable ATP dependent RNA helicase DDX4, VASA, VASA homolog, DDX4_HUMAN.

Background: ATP-dependent RNA helicase required during spermatogenesis (PubMed:10920202, PubMed:21034600). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (By similarity). Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (By similarity). Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs (By similarity).

ID gène: 54514

UniProt: Q9NQI0