RAB23 anticorps

N° du produit ABIN7091627

Détail du produit anti-RAB23 anticorps

Antigène: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAB23 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Homologie: Human,Mouse

Immunogène: Recombinant human RAB23 (Fragment) (His-tagged).

Clone: G6S4

Isotype: IgG1

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IF()

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RAB23

Antigène: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Autre désignation: RAB23 (RAB23 Produits)

Synonymes: anticorps MGC82152, anticorps hspc137, anticorps zgc:110261, anticorps AW545388, anticorps opb, anticorps opb2, anticorps HSPC137, anticorps Rab23-like, anticorps RAB23, member RAS oncogene family S homeolog, anticorps RAB23, member RAS oncogene family, anticorps ras-related protein Rab-23, anticorps rab23.S, anticorps RAB23, anticorps rab23, anticorps Rab23

Sujet:

Synonyms: DKFZp781H0695, HSPC137, MGC8900, Rab 23, RAB family small GTP binding protein RAB 23, RAB23, member RAS oncogene family, RAB23_HUMAN, Ras related protein Rab 23, Ras-related protein Rab-23.

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.

ID gène: 51715

UniProt: Q9ULC3

Pathways: Tube Formation