CD33 anticorps (AA 18-269)
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- Antigène Voir toutes CD33 Anticorps
- CD33
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Épitope
- AA 18-269
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD33 est non-conjugé
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Application
- Flow Cytometry (FACS), ELISA
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Immunogène
- Recombinant human CD33 (Asp18-His269) (ABIN6961110) produced by using human HEK293 cells
- Clone
- DM77
- Isotype
- IgG
- Top Product
- Discover our top product CD33 Anticorps primaire
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anti-CD33 (CD33) (AA 101-200) antibody
CD33 Reactivité: Humain, Souris FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-CD33 (CD33) (AA 15-237) antibodyCD33 Reactivité: Humain FACS, ELISA, IHC Hôte: Souris Monoclonal 2C6B7 unconjugated
anti-CD33 (CD33) (AA 18-240) antibodyCD33 Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-CD33 (CD33) (AA 49-259) antibodyCD33 Reactivité: Humain WB, IF, IHC Hôte: Lapin Polyclonal unconjugated
anti-CD33 (CD33) (AA 261-364) antibodyCD33 Reactivité: Humain FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-CD33 (CD33) (AA 1-364) antibodyCD33 Reactivité: Humain WB, ELISA, RNAi Hôte: Souris Monoclonal 2D12-G4 unconjugated
anti-CD33 (CD33) antibodyCD33 Reactivité: Humain, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, CyTOF Hôte: Souris Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibodyCD33 Reactivité: Humain, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, Func, CyTOF Hôte: Souris Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibody (Biotin)CD33 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal HIM3-4 Biotin
anti-CD33 (CD33) antibody (FITC)CD33 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal WM53 FITC
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- Indications d'application
- ELISA 1/5000-10000,Flow Cyt 1/100
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- CD33
- Autre désignation
- CD33 (CD33 Produits)
- Synonymes
- anticorps SIGLEC-3, anticorps SIGLEC3, anticorps p67, anticorps Siglec-3, anticorps gp67, anticorps CD33 molecule, anticorps CD33 antigen, anticorps CD33, anticorps Cd33
- Sujet
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Synonyms:CD33,SIGLEC3,gp67
Description:Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Preferentially recognizes and binds alpha-2,3- and more avidly alpha-2,6-linked sialic acid-bearing glycans. Upon engagement of ligands such as C1q or syalylated glycoproteins, two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) located in CD33 cytoplasmic tail are phosphorylated by Src-like kinases such as LCK. These phosphorylations provide docking sites for the recruitment and activation of protein-tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. In turn, these phosphatases regulate downstream pathways through dephosphorylation of signaling molecules. One of the repressive effect of CD33 on monocyte activation requires phosphoinositide 3-kinase/PI3K. - Poids moléculaire
- 39.8kDa
- ID gène
- 945
- UniProt
- P20138
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