L1CAM anticorps (AA 20-1120)

N° du produit ABIN7092955

Détail du produit anti-L1CAM anticorps

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Épitope: AA 20-1120

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp L1CAM est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human CD171(Ile20-Glu1120) (ABIN6964088) produced by using human HEK293 cells

Clone: DM155

Isotype: IgG

Information d'application

Indications d'application: ELISA 1/5000-10000,Flow Cyt 1/100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur L1CAM

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Autre désignation: CD171 (L1CAM Produits)

Sujet: Synonyms:CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1
Description:The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

Poids moléculaire: 140KDa

Pathways: Synaptic Membrane