BPI anticorps (AA 141-240) (Biotin)

N° du produit ABIN706513

Détail du produit anti-BPI anticorps (Biotin)

Antigène: BPI (Bactericidal/Permeability Increasing Protein (BPI))

Épitope: AA 141-240

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BPI est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BPI

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur BPI

Antigène: BPI (Bactericidal/Permeability Increasing Protein (BPI))

Autre désignation: BPI (BPI Produits)

Synonymes: anticorps 9230105K17Rik, anticorps Bpifd1, anticorps BPIFD1, anticorps rBPI, anticorps bpi, anticorps bpi.L, anticorps lbp, anticorps bactericidal/permeability-increasing protein, anticorps bactericidal permeablility increasing protein, anticorps bactericidal/permeability-increasing protein S homeolog, anticorps BPI, anticorps Bpi, anticorps bpi.S

Sujet:

Synonyms: Bactericidal permeability-increasing protein, bactericidal/permeability-increasing protein, BPI, CAP 57, BPI_HUMAN.

Background: The antimicrobial protein Bactericidal Permeability Increasing protein (BPI) is a 55 kDa protein found in the primary granules of polymorhonuclear leukocytes (PMN). The cytotoxicity action of BPI is limited to gram negative bacteria, reflecting the high affinity of BPI for bacterial LPS. Binding of BPI to live bacteria via LPS causes anti-infective activites: 1) cytotoxicity via sequential damage to bacterial outer and inner lipid membranes, 2) neutralization of gram-negative bacterial LPS, 3) opsonization of bacteria to enhance phagocytosis by neutrophils.

ID gène: 671