MACC1 anticorps (AA 761-852)
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- Antigène Voir toutes MACC1 Anticorps
- MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))
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Épitope
- AA 761-852
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MACC1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Rat
- Homologie
- Mouse,Cow
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human MACC1
- Isotype
- IgG
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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MACC‑1 antibody target therapy suppresses growth and migration of non‑small cell lung cancer." dans: Molecular medicine reports, Vol. 16, Issue 5, pp. 7329-7336, (2017) (PubMed).
: "Loss of zfp36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of zeb1, sox9 and macc1." dans: Oncotarget, Vol. 7, Issue 37, pp. 59144-59157, (2016) (PubMed).
: "Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells." dans: Molecular medicine reports, Vol. 12, Issue 3, pp. 3423-31, (2015) (PubMed).
: "Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer." dans: Oncology letters, Vol. 9, Issue 5, pp. 1989-1996, (2015) (PubMed).
: "Expression of MACC1 and c-Met in human gastric cancer and its clinical significance." dans: Cancer cell international, Vol. 13, Issue 1, pp. 121, (2013) (PubMed).
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MACC‑1 antibody target therapy suppresses growth and migration of non‑small cell lung cancer." dans: Molecular medicine reports, Vol. 16, Issue 5, pp. 7329-7336, (2017) (PubMed).
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- Antigène
- MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))
- Autre désignation
- MACC1 (MACC1 Produits)
- Sujet
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Synonyms: 7A5, SH3BP4L, Metastasis-associated in colon cancer protein 1, SH3 domain-containing protein 7a5, MACC1
Background: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.
- ID gène
- 346389
- UniProt
- Q6ZN28
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