HNRNPK anticorps (AA 201-300)
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- Antigène Voir toutes HNRNPK Anticorps
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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Épitope
- AA 201-300
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HNRNPK est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Cow,Pig,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human hnRNP K
- Isotype
- IgG
- Top Product
- Discover our top product HNRNPK Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- Autre désignation
- hnRNP K (HNRNPK Produits)
- Synonymes
- anticorps CSBP, anticorps HNRPK, anticorps TUNP, anticorps Csbp, anticorps Hnrpk, anticorps hnrpk, anticorps MGC75642, anticorps wu:fb37h02, anticorps wu:fi34c04, anticorps zgc:66162, anticorps KBBP, anticorps NOVA, anticorps heterogeneous nuclear ribonucleoprotein K, anticorps heterogeneous nuclear ribonucleoprotein K S homeolog, anticorps heterogeneous nuclear ribonucleoprotein k, anticorps HNRNPK, anticorps Hnrnpk, anticorps hnrnpk.S, anticorps hnrnpk, anticorps LOC5565718, anticorps CpipJ_CPIJ000130, anticorps NGK_p0004
- Sujet
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Synonyms: CSBP, TUNP, HNRPK, Heterogeneous nuclear ribonucleoprotein K, hnRNP K, Transformation up-regulated nuclear protein, HNRNPK
Background: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
- ID gène
- 3190
- UniProt
- P61978
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