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JAML anticorps

AMICA1 Reactivité: Humain WB, ELISA, FACS, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7111354
  • Antigène Voir toutes JAML (AMICA1) Anticorps
    JAML (AMICA1) (Adhesion Molecule, Interacts with CXADR Antigen 1 (AMICA1))
    Reactivité
    • 28
    • 5
    Humain
    Hôte
    • 17
    • 8
    • 3
    • 3
    • 2
    Lapin
    Clonalité
    • 21
    • 11
    Polyclonal
    Conjugué
    • 16
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Cet anticorp JAML est non-conjugé
    Application
    • 27
    • 21
    • 11
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    adhesion molecule, interacts with CXADR antigen 1
    Isotype
    IgG
    Top Product
    Discover our top product AMICA1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    JAML (AMICA1) (Adhesion Molecule, Interacts with CXADR Antigen 1 (AMICA1))
    Autre désignation
    JAML (AMICA1 Produits)
    Synonymes
    anticorps RGD1562572, anticorps AMICA, anticorps CREA7-1, anticorps CREA7-4, anticorps Gm638, anticorps JAML, anticorps Crea7, anticorps junction adhesion molecule like, anticorps Jaml, anticorps JAML
    Sujet
    Synonyms:AMICA1 Background:Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.
    Poids moléculaire
    30kd,44kd,50-60kd
    ID gène
    120425
    UniProt
    Q86YT9
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