ALKBH5 anticorps

N° du produit ABIN7111483

Détail du produit anti-ALKBH5 anticorps

Antigène: ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALKBH5 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: alkB, alkylation repair homolog 5(E. coli)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur ALKBH5

Antigène: ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))

Autre désignation: ALKBH5 (ALKBH5 Produits)

Synonymes: anticorps RGD1309496, anticorps ABH5, anticorps OFOXD, anticorps OFOXD1, anticorps AW050020, anticorps AW215868, anticorps Abh5, anticorps E130207K11, anticorps Ofoxd, anticorps alkB homolog 5, RNA demethylase, anticorps alkB homolog 5, RNA demethylase L homeolog, anticorps Alkbh5, anticorps alkbh5.L, anticorps ALKBH5

Sujet: Synonyms:ABH5, ALKBH5, FLJ20308, OFOXD, OFOXD1 Background:Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine(m6A) RNA, the most prevalent internal modification of messenger RNA(mRNA) in higher eukaryotes(PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA(in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron(PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export(PubMed:23177736). Required for spermatogenesis(By similarity).

Poids moléculaire: 51 kDa

ID gène: 54890

UniProt: Q6P6C2