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ANKRD15 anticorps

ANKRD15 Reactivité: Humain, Souris, Rat WB, ELISA, IF, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7111596
  • Antigène Voir toutes ANKRD15 Anticorps
    ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))
    Reactivité
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 10
    • 3
    Lapin
    Clonalité
    • 10
    • 3
    Polyclonal
    Conjugué
    • 10
    • 1
    • 1
    • 1
    Cet anticorp ANKRD15 est non-conjugé
    Application
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    KN motif and ankyrin repeat domains 1
    Isotype
    IgG
    Top Product
    Discover our top product ANKRD15 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))
    Autre désignation
    KANK1 (ANKRD15 Produits)
    Synonymes
    anticorps ANKRD15, anticorps CPSQ2, anticorps KANK, anticorps A930031B09Rik, anticorps AU015049, anticorps AW121052, anticorps Ankrd15, anticorps D330024H06Rik, anticorps mKIAA0172, anticorps KANK1, anticorps ankrd15, anticorps kank1.2, anticorps DMRT1, anticorps KN motif and ankyrin repeat domains 1, anticorps KN motif and ankyrin repeat domains 1 L homeolog, anticorps doublesex and mab-3 related transcription factor 1, anticorps KANK1, anticorps Kank1, anticorps kank1.L, anticorps DMRT1
    Sujet
    Synonyms:ANKRD15, KANK, KIAA0172 Background:Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity, the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia, the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading, the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.
    Poids moléculaire
    75-85kd,30kd
    ID gène
    23189
    UniProt
    Q14678
    Pathways
    Regulation of Actin Filament Polymerization
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