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BBS1 anticorps

BBS1 Reactivité: Humain, Souris ELISA, WB, IF, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7111930
  • Antigène Voir toutes BBS1 Anticorps
    BBS1 (Bardet-Biedl Syndrome 1 (BBS1))
    Reactivité
    • 22
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 20
    • 1
    • 1
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BBS1 est non-conjugé
    Application
    • 11
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    Bardet-Biedl syndrome 1
    Isotype
    IgG
    Top Product
    Discover our top product BBS1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:1000, IP: 1:500-1:1000, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    BBS1 (Bardet-Biedl Syndrome 1 (BBS1))
    Autre désignation
    BBS1 (BBS1 Produits)
    Synonymes
    anticorps im:7144669, anticorps bbs2l2, anticorps BBS1, anticorps DKFZp468B1612, anticorps BBS2L2, anticorps AI451249, anticorps D19Ertd609e, anticorps Bardet-Biedl syndrome 1, anticorps bardet-biedl syndrome 1, anticorps Bardet-Biedl syndrome 1 (human), anticorps BBS1, anticorps bbs1, anticorps Bbs1
    Sujet
    Synonyms:Bardet Biedl syndrome 1, BBS1, BBS2 like protein 2, BBS2L2 Background:The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog(SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
    Poids moléculaire
    65 kDa
    ID gène
    582
    UniProt
    Q8NFJ9
    Pathways
    Signalisation Hedgehog
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