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BBS2 anticorps

BBS2 Reactivité: Humain, Chien WB, ELISA, IF Hôte: Souris Monoclonal 9F10 unconjugated
N° du produit ABIN7111932
  • Antigène Voir toutes BBS2 Anticorps
    BBS2 (Bardet-Biedl Syndrome 2 (BBS2))
    Reactivité
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Chien
    Hôte
    • 9
    • 2
    Souris
    Clonalité
    • 11
    Monoclonal
    Conjugué
    • 11
    Cet anticorp BBS2 est non-conjugé
    Application
    • 11
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purification
    Protein A+G purification
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    Bardet-Biedl syndrome 2
    Clone
    9F10
    Isotype
    IgG2a
    Top Product
    Discover our top product BBS2 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    BBS2 (Bardet-Biedl Syndrome 2 (BBS2))
    Autre désignation
    BBS2 (BBS2 Produits)
    Synonymes
    anticorps fb80a05, anticorps wu:fb80a05, anticorps DKFZp468B105, anticorps DKFZp469L0919, anticorps BBS, anticorps 2410125H22Rik, anticorps AI447581, anticorps Bardet-Biedl syndrome 2, anticorps bardet-biedl syndrome 2, anticorps Bardet-Biedl syndrome 2 (human), anticorps bbs2, anticorps BBS2, anticorps Bbs2
    Sujet
    Synonyms: Background:The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog(SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
    Poids moléculaire
    80 kDa
    ID gène
    583
    UniProt
    Q9BXC9
    Pathways
    Signalisation Hedgehog
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