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BBS7 anticorps

BBS7 Reactivité: Humain, Souris WB, ELISA, IHC, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7111938
  • Antigène Voir toutes BBS7 Anticorps
    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
    Reactivité
    • 30
    • 2
    • 2
    Humain, Souris
    Hôte
    • 26
    • 3
    • 1
    Lapin
    Clonalité
    • 28
    • 2
    Polyclonal
    Conjugué
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp BBS7 est non-conjugé
    Application
    • 25
    • 19
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    Bardet-Biedl syndrome 7
    Isotype
    IgG
    Top Product
    Discover our top product BBS7 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000, IP: 1:500-1:1000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
    Autre désignation
    BBS7 (BBS7 Produits)
    Synonymes
    anticorps BBS7, anticorps bbs2l1, anticorps BBS2L1, anticorps id:ibd5048, anticorps zgc:153772, anticorps 8430406N16Rik, anticorps Bardet-Biedl syndrome 7, anticorps bardet-biedl syndrome 7, anticorps Bardet-Biedl syndrome 7 L homeolog, anticorps Bardet-Biedl syndrome 7 (human), anticorps BBS7, anticorps bbs7, anticorps MICPUN_100192, anticorps MICPUCDRAFT_16331, anticorps bbs7.L, anticorps Bbs7
    Sujet
    Synonyms:BBS2L1 Background:The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog(SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
    Poids moléculaire
    80 kDa
    ID gène
    55212
    UniProt
    Q8IWZ6
    Pathways
    Signalisation Hedgehog
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