anticorps BHLHB8, anticorps MIST1, anticorps 1810009C13Rik, anticorps Bhlhb8, anticorps MIST-1, anticorps Mist1, anticorps bHlH, anticorps basic helix-loop-helix family member a15, anticorps basic helix-loop-helix family, member a15, anticorps BHLHA15, anticorps Bhlha15
Sujet
Synonyms:BHLHB8, MIST1 Background:Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'(By similarity).