Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

BHLHE22 anticorps

BHLHE22 Reactivité: Humain, Souris WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7111942
  • Antigène Voir toutes BHLHE22 Anticorps
    BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))
    Reactivité
    • 21
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 18
    • 2
    • 1
    Lapin
    Clonalité
    • 21
    Polyclonal
    Conjugué
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp BHLHE22 est non-conjugé
    Application
    • 21
    • 15
    • 12
    • 12
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    basic helix-loop-helix family, member e22
    Isotype
    IgG
    Top Product
    Discover our top product BHLHE22 Anticorps primaire
  • Indications d'application
    WB: 1:200-1:1000, IF: 1:10-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))
    Autre désignation
    BHLHE22 (BHLHE22 Produits)
    Synonymes
    anticorps bhlhb5, anticorps MGC145865, anticorps BHLHE22, anticorps Beta3.1, anticorps wu:fq25e11, anticorps zgc:64225, anticorps BHLHB5, anticorps Beta3, anticorps CAGL85, anticorps TNRC20, anticorps Bhlhb5, anticorps basic helix-loop-helix family member e22, anticorps basic helix-loop-helix family, member e22, anticorps bhlhe22, anticorps BHLHE22, anticorps Bhlhe22
    Sujet
    Synonyms:BHLHB5, TNRC20 Background:Inhibits DNA binding of TCF3/E47 homodimers and TCF3(E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA(By similarity). In the brain, may function as an area-specific transcription factor that regulates the postmitotic acquisition of area identities and elucidate the genetic hierarchy between progenitors and postmitotic neurons driving neocortical arealization. May be required for the survival of a specific population of inhibitory neurons in the superficial laminae of the spinal chord dorsal horn that may regulate pruritis. Seems to play a crucial role in the retinogenesis, in the specification of amacrine and bipolar subtypes. Forms with PRDM8 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation.
    Poids moléculaire
    37 kDa
    ID gène
    27319
    UniProt
    Q8NFJ8
Vous êtes ici:
Support technique