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BVES anticorps

BVES Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7112013
  • Antigène Voir toutes BVES Anticorps
    BVES (Blood Vessel Epicardial Substance (BVES))
    Reactivité
    • 31
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 28
    • 3
    Lapin
    Clonalité
    • 29
    • 2
    Polyclonal
    Conjugué
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BVES est non-conjugé
    Application
    • 23
    • 18
    • 14
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    blood vessel epicardial substance
    Isotype
    IgG
    Top Product
    Discover our top product BVES Anticorps primaire
  • Indications d'application
    WB: 1:100-1:1000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    BVES (Blood Vessel Epicardial Substance (BVES))
    Autre désignation
    BVES (BVES Produits)
    Synonymes
    anticorps HBVES, anticorps POP1, anticorps POPDC1, anticorps Pop1, anticorps Popdc1, anticorps mBVES, anticorps Popeye-1, anticorps Xbves, anticorps Xbves-A, anticorps Xpop-1, anticorps Xpop-1-A, anticorps pop-1, anticorps pop1, anticorps pop1-A, anticorps popdc1, anticorps popdc1-A, anticorps zgc:86887, anticorps BVES, anticorps Xpop-1-B, anticorps bves, anticorps pop1-B, anticorps popdc1-B, anticorps hbves, anticorps blood vessel epicardial substance, anticorps blood vessel epicardial substance L homeolog, anticorps blood vessel epicardial substance S homeolog, anticorps BVES, anticorps Bves, anticorps bves.L, anticorps bves, anticorps bves.S
    Sujet
    Synonyms:BVES, HBVES, POP1, POPDC1, Popeye protein 1 Background:Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction(TJ) paracellular permeability barrier in epithelial cells(PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading(By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density(PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
    Poids moléculaire
    41-70 kDa
    ID gène
    11149
    UniProt
    Q8NE79
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