BVES anticorps
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- Antigène Voir toutes BVES Anticorps
- BVES (Blood Vessel Epicardial Substance (BVES))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BVES est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- blood vessel epicardial substance
- Isotype
- IgG
- Top Product
- Discover our top product BVES Anticorps primaire
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- Indications d'application
- WB: 1:100-1:1000, IHC: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- BVES (Blood Vessel Epicardial Substance (BVES))
- Autre désignation
- BVES (BVES Produits)
- Synonymes
- anticorps HBVES, anticorps POP1, anticorps POPDC1, anticorps Pop1, anticorps Popdc1, anticorps mBVES, anticorps Popeye-1, anticorps Xbves, anticorps Xbves-A, anticorps Xpop-1, anticorps Xpop-1-A, anticorps pop-1, anticorps pop1, anticorps pop1-A, anticorps popdc1, anticorps popdc1-A, anticorps zgc:86887, anticorps BVES, anticorps Xpop-1-B, anticorps bves, anticorps pop1-B, anticorps popdc1-B, anticorps hbves, anticorps blood vessel epicardial substance, anticorps blood vessel epicardial substance L homeolog, anticorps blood vessel epicardial substance S homeolog, anticorps BVES, anticorps Bves, anticorps bves.L, anticorps bves, anticorps bves.S
- Sujet
- Synonyms:BVES, HBVES, POP1, POPDC1, Popeye protein 1 Background:Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction(TJ) paracellular permeability barrier in epithelial cells(PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading(By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density(PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
- Poids moléculaire
- 41-70 kDa
- ID gène
- 11149
- UniProt
- Q8NE79
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