BRD7 anticorps
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- Antigène Voir toutes BRD7 Anticorps
- BRD7 (Bromodomain Containing 7 (BRD7))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BRD7 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- bromodomain containing 7
- Isotype
- IgG
- Top Product
- Discover our top product BRD7 Anticorps primaire
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anti-Bromodomain Containing 7 (BRD7) (Internal Region) antibody
BRD7 Reactivité: Humain, Souris, Rat WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 1-95) antibodyBRD7 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (C-Term) antibodyBRD7 Reactivité: Humain, Rat, Chien, Cobaye, Cheval, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 601-651) antibodyBRD7 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 387-418) antibodyBRD7 Reactivité: Souris WB Hôte: Lapin Polyclonal RB43270 unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 514-567) antibodyBRD7 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 77-106), (N-Term) antibodyBRD7 Reactivité: Souris WB Hôte: Lapin Polyclonal RB32783 unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 1-651) antibodyBRD7 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (C-Term) antibodyBRD7 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- BRD7 (Bromodomain Containing 7 (BRD7))
- Autre désignation
- BRD7 (BRD7 Produits)
- Sujet
- Synonyms:BP75, CELTIX1 Background:Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR(By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9'(H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.
- Poids moléculaire
- 70-74kd
- ID gène
- 29117
- UniProt
- Q9NPI1
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