CTSC anticorps

N° du produit ABIN7112397

Détail du produit anti-CTSC anticorps

Antigène: CTSC (Cathepsin C (CTSC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTSC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Cathepsin C

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur CTSC

Antigène: CTSC (Cathepsin C (CTSC))

Autre désignation: CTSC (CTSC Produits)

Synonymes: anticorps CPPI, anticorps DPP-I, anticorps DPP1, anticorps DPPI, anticorps HMS, anticorps JP, anticorps JPD, anticorps PALS, anticorps PDON1, anticorps PLS, anticorps MGC69126, anticorps MGC107782, anticorps AI047818, anticorps CATC, anticorps cb912, anticorps ik:tdsubc_1h2, anticorps sb:cb146, anticorps wu:fb34g12, anticorps wu:fj58d01, anticorps cathepsin C, anticorps cathepsin C L homeolog, anticorps cathepsin CPC1, anticorps CTSC, anticorps ctsc.L, anticorps ctsc, anticorps TP03_0357, anticorps CMU_003360, anticorps CPC1, anticorps NAEGRDRAFT_80477, anticorps NAEGRDRAFT_37577, anticorps Ctsc, anticorps Smp_183330

Sujet: Synonyms:CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS Background:This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

Poids moléculaire: 70 kDa

ID gène: 1075

UniProt: P53634