CISD2 anticorps

N° du produit ABIN7112541

Détail du produit anti-CISD2 anticorps

Antigène: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CISD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: CDGSH iron sulfur domain 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur CISD2

Antigène: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Autre désignation: CISD2 (CISD2 Produits)

Synonymes: anticorps ERIS, anticorps Miner1, anticorps NAF-1, anticorps WFS2, anticorps ZCD2, anticorps 1500009M05Rik, anticorps 1500026J14Rik, anticorps 1500031D15Rik, anticorps AI848398, anticorps B630006A20Rik, anticorps Noxp70, anticorps Zcd2, anticorps RGD1566242, anticorps zgc:64148, anticorps eris, anticorps miner1, anticorps wfs2, anticorps zcd2, anticorps cisd2, anticorps BcDNA:RE49709, anticorps Dmel\\CG1458, anticorps CDGSH iron sulfur domain 2, anticorps CDGSH iron sulfur domain 2 L homeolog, anticorps CDGSH iron sulfur domain 2 S homeolog, anticorps CISD2, anticorps Cisd2, anticorps cisd2, anticorps cisd2.L, anticorps cisd2.S

Sujet: Synonyms:CDGSH2, ERIS, ZCD2 Background:Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.

Poids moléculaire: 13-15 kDa

ID gène: 493856

UniProt: Q8N5K1

Pathways: Activation of Innate immune Response