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CDKN1B anticorps
CDKN1B
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC, IF, IP
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN7113177
Détail du produit anti-CDKN1B anticorps
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Antigène
Voir toutes CDKN1B Anticorps
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Reactivité
Toutes les réactivités sur CDKN1B Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur CDKN1B Anticorps
Lapin
Clonalité
Toutes les clonalités sur CDKN1B Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CDKN1B Anticorps
Cet anticorp CDKN1B est non-conjugé
Application
Tous les applications à travers CDKN1B Anticorps.
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
Purification
Immunogen affinity purified
Pureté
≥95 % as determined by SDS-PAGE
Immunogène
cyclin-dependent kinase inhibitor 1B(p27, Kip1)
Isotype
IgG
Top Product
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Alternatives
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Information d'application
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Indications d'application
WB: 1:200-1:2000, IP: 1:200-1:1000, IHC: 1:50-1:500, IF: 1:50-1:500
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Date de péremption
12 months
Détails sur CDKN1B
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Antigène
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Autre désignation
P27, KIP1 (CDKN1B Produits )
Synonymes
anticorps CDKN4, anticorps KIP1, anticorps MEN1B, anticorps MEN4, anticorps P27KIP1, anticorps cdkn1b, anticorps sb:cb611, anticorps wu:fb63g10, anticorps wu:fb64g10, anticorps wu:fe18e03, anticorps CDKN1B, anticorps Kip1, anticorps p27, anticorps FAM14D, anticorps ISG12, anticorps ISG12A, anticorps P27, anticorps Cdki1b, anticorps AA408329, anticorps AI843786, anticorps p27Kip1, anticorps cdkn1bl, anticorps cyclin dependent kinase inhibitor 1B, anticorps cyclin-dependent kinase inhibitor 1Bb, anticorps interferon alpha inducible protein 27, anticorps cyclin-dependent kinase inhibitor 1B, anticorps cyclin-dependent kinase inhibitor 1Ba, anticorps CDKN1B, anticorps cdkn1bb, anticorps IFI27, anticorps Cdkn1b, anticorps cdkn1ba
Sujet
Synonyms:CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27, P27, KIP1, P27KIP1 Background:CDKN1B, also named as P27 or KIP1, is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. P27 binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controlling cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Downregulation of P27 has been implicated in the progression of several malignancies, including lung cancer, hepatocellular carcinoma, salivary cancer, oral squamous cell carcinomas, and gastric cancer.
Poids moléculaire
27 kDa
ID gène
1027
UniProt
P46527
Pathways
Cycle Cellulaire , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Negative Regulation of Hormone Secretion , Sensory Perception of Sound , Mitotic G1-G1/S Phases , DNA Replication , Positive Regulation of Endopeptidase Activity , Synthesis of DNA , Autophagy
Vus récemment
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