DACH2 anticorps

N° du produit ABIN7113311

Détail du produit anti-DACH2 anticorps

Antigène: DACH2 (Dachshund 2 (DACH2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DACH2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: dachshund homolog 2(Drosophila)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur DACH2

Antigène: DACH2 (Dachshund 2 (DACH2))

Autre désignation: DACH2 (DACH2 Produits)

Synonymes: anticorps 9430028N04Rik, anticorps RGD1561687, anticorps dachshund family transcription factor 2, anticorps dachshund 2 (Drosophila), anticorps dachshund family transcription factor 2 L homeolog, anticorps dachshund homolog 2, anticorps dachshund homolog 2 (Drosophila), anticorps DACH2, anticorps Dach2, anticorps dach2.L, anticorps LOC612847, anticorps dach2

Sujet: Synonyms: Background:Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression(By similarity). Probably binds to DNA via its DACHbox-N domain.

Poids moléculaire: 65 kDa

ID gène: 117154

UniProt: Q96NX9