DHX36 anticorps

N° du produit ABIN7113365

Détail du produit anti-DHX36 anticorps

Antigène: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX36 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: DEAH(Asp-Glu-Ala-His) box polypeptide 36

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur DHX36

Antigène: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Autre désignation: DHX36 (DHX36 Produits)

Synonymes: anticorps DHX57, anticorps DDX36, anticorps G4R1, anticorps MLEL1, anticorps RHAU, anticorps 2810407E23Rik, anticorps AI452301, anticorps AU022184, anticorps Ddx36, anticorps mKIAA1488, anticorps DEAH-box helicase 36, anticorps ATP-dependent RNA helicase DHX36, anticorps DEAH (Asp-Glu-Ala-His) box polypeptide 36, anticorps Dhx36, anticorps DHX36, anticorps dhx36, anticorps LOC100456222, anticorps LOC100633205

Sujet: Synonyms:DDX36, KIAA1488, MLEL1, RHAU Background:Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component(TERC) 5'-end(nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation, the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.

Poids moléculaire: 120 kDa

ID gène: 170506

UniProt: Q9H2U1

Pathways: Toll-Like Receptors Cascades