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DOCK7 anticorps

DOCK7 Reactivité: Humain, Rat, Souris ELISA, WB, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7113381
  • Antigène Voir toutes DOCK7 Anticorps
    DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
    Reactivité
    • 35
    • 16
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Rat, Souris
    Hôte
    • 33
    • 2
    Lapin
    Clonalité
    • 35
    Polyclonal
    Conjugué
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DOCK7 est non-conjugé
    Application
    • 13
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    dedicator of cytokinesis 7
    Isotype
    IgG
    Top Product
    Discover our top product DOCK7 Anticorps primaire
  • Indications d'application
    WB: 1:200-1:1000, IP: 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
    Autre désignation
    DOCK7 (DOCK7 Produits)
    Synonymes
    anticorps im:7145816, anticorps im:7157388, anticorps wu:fb93h07, anticorps ZIR2, anticorps 3110056M06Rik, anticorps Gm430, anticorps m, anticorps mKIAA1771, anticorps dedicator of cytokinesis 7, anticorps dedicator of cytokinesis protein 7, anticorps dedicator of cytokinesis 6, anticorps DOCK7, anticorps dock7, anticorps NAEGRDRAFT_56982, anticorps LOC100185115, anticorps dock6, anticorps Dock7
    Sujet
    Synonyms:dedicator of cytokinesis 7, DOCK7, KIAA1771, ZIR2 Background:Functions as a guanine nucleotide exchange factor(GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization(PubMed:16982419). Has a role in pigmentation(By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells(RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3(By similarity).Multiple isoforms of DOCK 7 exist due to alternative splicing events. This DOCK 7 antibody can recognize all the isoforms.
    Poids moléculaire
    240 kDa
    ID gène
    85440
    UniProt
    Q96N67
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