DOC2B anticorps

N° du produit ABIN7113615

Détail du produit anti-DOC2B anticorps

Antigène: DOC2B (Double C2-Like Domains, beta (DOC2B))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOC2B est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: double C2-like domains, beta

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur DOC2B

Antigène: DOC2B (Double C2-Like Domains, beta (DOC2B))

Autre désignation: DOC2B (DOC2B Produits)

Synonymes: anticorps DOC2BL, anticorps multiple C2 and transmembrane domain-containing protein 1-like, anticorps double C2 domain beta, anticorps double C2-like domains, beta, anticorps double C2, beta, anticorps LOC100369196, anticorps DOC2B, anticorps doc2b, anticorps Doc2b

Sujet: Synonyms:DOC2BL Background:Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes(By similarity).

Poids moléculaire: 46kd

ID gène: 8447

UniProt: Q14184

Pathways: Positive Regulation of Peptide Hormone Secretion