EHD1 anticorps

N° du produit ABIN7113753

Détail du produit anti-EHD1 anticorps

Antigène: EHD1 (EH-Domain Containing 1 (EHD1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EHD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: EH-domain containing 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur EHD1

Antigène: EHD1 (EH-Domain Containing 1 (EHD1))

Autre désignation: EHD1 (EHD1 Produits)

Synonymes: anticorps AA409636, anticorps Past1, anticorps RME-1, anticorps RGD1306960, anticorps cb862, anticorps ehd1, anticorps ehd3, anticorps ehd3l, anticorps wu:fb95h05, anticorps zgc:92331, anticorps MGC130676, anticorps Testilin, anticorps H-PAST, anticorps HPAST1, anticorps PAST, anticorps PAST1, anticorps zgc:77049, anticorps EH-domain containing 1, anticorps EH-domain containing 1b, anticorps EH domain containing 1 L homeolog, anticorps EH domain-containing protein 1, anticorps EH domain containing 1, anticorps EH-domain containing 1a, anticorps Ehd1, anticorps ehd1b, anticorps ehd1.L, anticorps EHD1, anticorps LOC585665, anticorps LOC100091823, anticorps ehd1a

Sujet: Synonyms:PAST, Background:ATP-and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes(PubMed:24019528). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes(PubMed:15020713, PubMed:17233914, PubMed:20801876). Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth(By similarity). Plays a role in myoblast fusion(By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing(By similarity). Plays a role in the formation of the ciliary vesicle(CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles(DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis(PubMed:25686250).

Poids moléculaire: 61 kDa

ID gène: 10938

UniProt: Q9H4M9

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development