anticorps C20orf31, anticorps C20orf49, anticorps bA4204.1, anticorps 9530090G24Rik, anticorps AI327354, anticorps RGD1303074, anticorps MGC88910, anticorps DKFZp459A0314, anticorps ER degradation enhancing alpha-mannosidase like protein 2, anticorps ER degradation enhancer, mannosidase alpha-like 2, anticorps EDEM2, anticorps Edem2, anticorps edem2
Sujet
Synonyms:C20orf31, C20orf49 Background:Initiates the endoplasmic reticulum-associated degradation(ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2(PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.