EIF3E anticorps
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- Antigène Voir toutes EIF3E Anticorps
- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EIF3E est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- eukaryotic translation initiation factor 3, subunit E
- Isotype
- IgG
- Top Product
- Discover our top product EIF3E Anticorps primaire
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- Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
- Autre désignation
- EIF3E (EIF3E Produits)
- Synonymes
- anticorps EIF3-P48, anticorps EIF3S6, anticorps INT6, anticorps eIF3-p46, anticorps 48kDa, anticorps Eif3s6, anticorps Int6, anticorps eIF3-p48, anticorps eif3-p48, anticorps eif3s6, anticorps eif3s6-A, anticorps eIF3e, anticorps eIF3-S6, anticorps eif3s6-B, anticorps EIF3SE, anticorps eif3s6b, anticorps im:7147439, anticorps QtsA-18056, anticorps eukaryotic translation initiation factor 3 subunit E, anticorps eukaryotic translation initiation factor 3, subunit E, anticorps eukaryotic translation initiation factor 3 subunit E L homeolog, anticorps eukaryotic translation initiation factor 3 subunit 6, anticorps eukaryotic translation initiation factor 3 subunit E S homeolog, anticorps eukaryotic translation initiation factor 3, subunit E, a, anticorps Eukaryotic translation initiation factor 3 subunit E, anticorps eukaryotic translation initiation factor 3, subunit E, b, anticorps EIF3E, anticorps Eif3e, anticorps eif3e, anticorps eif3e.L, anticorps LOC692936, anticorps eif3e.S, anticorps eif3ea, anticorps eif-3.E, anticorps eif3eb, anticorps LOC108348260, anticorps int6
- Sujet
- Synonyms:EIF3S6, Background:Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay(NMD), may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
- Poids moléculaire
- 48-52kd
- ID gène
- 3646
- UniProt
- P60228
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
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