eIF4EBP2 anticorps

N° du produit ABIN7113973

Détail du produit anti-eIF4EBP2 anticorps

Antigène: eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp eIF4EBP2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: eukaryotic translation initiation factor 4E binding protein 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur eIF4EBP2

Antigène: eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))

Autre désignation: EIF4EBP2 (EIF4EBP2 Produits)

Synonymes: anticorps 4ebp2, anticorps MGC75579, anticorps wu:fa55e11, anticorps wu:fp45e09, anticorps MGC78987, anticorps EIF4EBP2, anticorps eIF-4E, anticorps Tb06.28P18.1010, anticorps 4EBP2, anticorps PHASII, anticorps 2810011I19Rik, anticorps 4E-BP2, anticorps AA792569, anticorps BC010348, anticorps PHAS-II, anticorps eukaryotic translation initiation factor 4E binding protein 2, anticorps eukaryotic translation initiation factor 4E binding protein 2 L homeolog, anticorps eukaryotic initiation factor 4E, anticorps eukaryotic translation initiation factor 4E, anticorps putative eukaryotic translation initiation factor 4e, anticorps eif4ebp2, anticorps Eif4ebp2, anticorps eif4ebp2.L, anticorps EIF4EBP2, anticorps eIF-4E, anticorps Tb927.6.1870, anticorps LMJF_30_0450

Sujet: Synonyms: Background:Repressor of translation initiation involved in synaptic plasticity, learning and memory formation(By similarity). Regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form of EIF4EBP2 competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation(PubMed:25533957). EIF4EBP2 is enriched in brain and acts as a regulator of synapse activity and neuronal stem cell renewal via its ability to repress translation initiation(By similarity). Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways(By similarity).

Poids moléculaire: ~20 kDa

ID gène: 1979

UniProt: Q13542