ERI1 anticorps
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- Antigène Voir toutes ERI1 Anticorps
- ERI1 (Exoribonuclease 1 (ERI1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ERI1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- exoribonuclease 1
- Isotype
- IgG
- Top Product
- Discover our top product ERI1 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- ERI1 (Exoribonuclease 1 (ERI1))
- Autre désignation
- ERI1 (ERI1 Produits)
- Synonymes
- anticorps THEX1, anticorps thex1, anticorps zgc:110635, anticorps hexo, anticorps Eri-1, anticorps 3'HEXO, anticorps HEXO, anticorps 3'hexo, anticorps 3110010F15Rik, anticorps Thex1, anticorps eri-1, anticorps RGD1308378, anticorps exoribonuclease 1, anticorps three prime repair exonuclease 1, anticorps exoribonuclease 1 L homeolog, anticorps 3'-5' exonuclease eri-1, anticorps ERI1, anticorps CpipJ_CPIJ003945, anticorps eri1, anticorps eri1.L, anticorps Eri1, anticorps eri-1
- Sujet
- Synonyms:3'EXO, THEX1 Background:RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs(siRNAs) in vitro, suggesting a possible role as regulator of RNA interference(RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
- Poids moléculaire
- 46kd
- ID gène
- 90459
- UniProt
- Q8IV48
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