Exportin 7 anticorps

N° du produit ABIN7114023

Détail du produit anti-Exportin 7 anticorps

Antigène: Exportin 7 (XPO7)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Exportin 7 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: exportin 7

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Exportin 7

Antigène: Exportin 7 (XPO7)

Autre désignation: XPO7 (XPO7 Produits)

Synonymes: anticorps EXP7, anticorps RANBP16, anticorps exportin-7, anticorps ranbp16, anticorps xpo7, anticorps xpo7-b, anticorps MGC98303, anticorps Exportin-7, anticorps DKFZp469N246, anticorps 4930506C02Rik, anticorps BB164534, anticorps Ranbp16, anticorps mKIAA0745, anticorps CG33180, anticorps CG9126, anticorps CG9136, anticorps Dmel\\CG33180, anticorps RanBP16, anticorps exportin 7, anticorps exportin 7 S homeolog, anticorps exportin 7 L homeolog, anticorps CG33180 gene product from transcript CG33180-RE, anticorps XPO7, anticorps Xpo7, anticorps xpo7, anticorps xpo7.S, anticorps xpo7.L, anticorps Ranbp16

Sujet: Synonyms:Exp7, exportin 7, KIAA0745, Ran binding protein 16, RANBP16, XPO7 Background:Mediates the nuclear export of proteins(cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex(NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP(induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus.

Poids moléculaire: 100 kDa

ID gène: 23039

UniProt: Q9UIA9