FBXO7 anticorps

N° du produit ABIN7114054

Détail du produit anti-FBXO7 anticorps

Antigène: FBXO7 (F-Box Protein 7 (FBXO7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: F-box protein 7

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur FBXO7

Antigène: FBXO7 (F-Box Protein 7 (FBXO7))

Autre désignation: FBXO7 (FBXO7 Produits)

Synonymes: anticorps fbxo7, anticorps MGC80085, anticorps FBXO7, anticorps fbx7, anticorps MGC135804, anticorps MGC145325, anticorps ATFBP7, anticorps F-BOX PROTEIN 7, anticorps F-box protein 7, anticorps F8K7.20, anticorps F8K7_20, anticorps DKFZp469H0739, anticorps si:ch211-286m4.2, anticorps zgc:114096, anticorps FBX, anticorps FBX07, anticorps FBX7, anticorps PARK15, anticorps PKPS, anticorps 2410015K21Rik, anticorps A230052G17Rik, anticorps AI117679, anticorps AW260462, anticorps C85118, anticorps F-box protein 7, anticorps F-box protein 7 L homeolog, anticorps FBXO7, anticorps fbxo7.L, anticorps fbxo7, anticorps FBP7, anticorps Fbxo7

Sujet: Synonyms:FBX7 Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy(mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.

Poids moléculaire: 58.5 kDa

ID gène: 25793

UniProt: Q9Y3I1