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Glutaredoxin 2 anticorps

GRX2 Reactivité: Humain, Rat, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7114635
  • Antigène Voir toutes Glutaredoxin 2 (GRX2) Anticorps
    Glutaredoxin 2 (GRX2)
    Reactivité
    • 45
    • 22
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Rat, Souris
    Hôte
    • 39
    • 6
    Lapin
    Clonalité
    • 43
    • 2
    Polyclonal
    Conjugué
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Glutaredoxin 2 est non-conjugé
    Application
    • 32
    • 21
    • 13
    • 13
    • 9
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    glutaredoxin 2
    Isotype
    IgG
    Top Product
    Discover our top product GRX2 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    Glutaredoxin 2 (GRX2)
    Autre désignation
    GLRX2 (GRX2 Produits)
    Synonymes
    anticorps ECK1049, anticorps JW1051, anticorps CGI-133, anticorps GRX2, anticorps 1700010P22Rik, anticorps AI645710, anticorps Grx2, anticorps glutaredoxin 2 (Grx2), anticorps glutaredoxin Grx2, anticorps thioredoxin, anticorps glutaredoxin 2, anticorps glutaredoxin 2 (thioltransferase), anticorps grxB, anticorps grx2, anticorps AF_RS10790, anticorps GLRX2, anticorps Glrx2
    Sujet
    Synonyms:GRX2 Background:Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione(GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
    Poids moléculaire
    16 kDa
    ID gène
    51022
    UniProt
    Q9NS18
    Pathways
    Cell RedoxHomeostasis
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