anticorps H2A/R, anticorps histone cluster 2 H2A family member a4, anticorps HIST2H2AA4
Sujet
Synonyms:H2AFO, HIST2H2AA Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.