HORMAD1 anticorps

N° du produit ABIN7115109

Détail du produit anti-HORMAD1 anticorps

Antigène: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HORMAD1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: HORMA domain containing 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur HORMAD1

Antigène: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Autre désignation: HORMAD1 (HORMAD1 Produits)

Synonymes: anticorps CT46, anticorps NOHMA, anticorps 4921522K05Rik, anticorps Nohma, anticorps RGD1564960, anticorps zgc:92129, anticorps HORMAD1, anticorps HORMA domain containing 1, anticorps HORMA domain containing 1 S homeolog, anticorps HORMAD1, anticorps Hormad1, anticorps hormad1, anticorps hormad1.S

Sujet: Synonyms:NOHMA Background:Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks(DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin(MSUC) and meiotic prophase quality control in both sexes(By similarity).

Poids moléculaire: 45 kDa

ID gène: 84072

UniProt: Q86X24

Pathways: M Phase