anticorps ZAS1, anticorps CIRIP, anticorps MBP-1, anticorps ZNF40, anticorps CRYBP1, anticorps ZNF40A, anticorps PRDII-BF1, anticorps Schnurri-1, anticorps Cryabp1, anticorps Shn1, anticorps xhivep1, anticorps schnurri, anticorps si:dkey-184j23.2, anticorps si:dkey-31k9.2, anticorps human immunodeficiency virus type I enhancer binding protein 1, anticorps human immunodeficiency virus type I enhancer binding protein 1 S homeolog, anticorps HIVEP1, anticorps Hivep1, anticorps hivep1.S, anticorps hivep1
Sujet
Synonyms:ZNF40 Background:This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS(IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.