INSIG1 anticorps
-
- Antigène Voir toutes INSIG1 Anticorps
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp INSIG1 est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- insulin induced gene 1
- Isotype
- IgG
- Top Product
- Discover our top product INSIG1 Anticorps primaire
-
anti-Insulin Induced Gene 1 (INSIG1) (AA 1-87) antibody
INSIG1 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 36-63), (N-Term) antibodyINSIG1 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB21689 unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Internal Region) antibodyINSIG1 Reactivité: Humain, Souris WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 63-112) antibodyINSIG1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Lapin, Chien, Cobaye, Porc, Singe, Hamster, Xenopus laevis, Roussette (Chauve-souris), Poulet WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Lapin, Chien, Cobaye, Mouton, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (C-Term) antibodyINSIG1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 71-120) antibodyINSIG1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Lapin, Mouton, Porc, Hamster, Xenopus laevis WB Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (C-Term) antibodyINSIG1 Reactivité: Humain, Singe WB Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Lapin, Chien, Cobaye, Mouton, Porc, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
-
- Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
-
- Antigène
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
- Autre désignation
- INSIG1 (INSIG1 Produits)
- Sujet
- Synonyms:CL 6, INSIG 1, INSIG1, insulin induced gene 1, Insulin induced gene 1 protein Background:Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins(SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation(ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78. May play a role in growth and differentiation of tissues involved in metabolic control. May play a regulatory role during G0/G1 transition of cell growth.
- Poids moléculaire
- 28-31, 66-70 kDa
- ID gène
- 3638
- UniProt
- O15503
- Pathways
- ER-Nucleus Signaling
-
