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INTS3 anticorps

INTS3 Reactivité: Humain, Souris, Rat WB, ELISA, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7115305
  • Antigène Voir toutes INTS3 Anticorps
    INTS3 (Integrator Complex Subunit 3 (INTS3))
    Reactivité
    • 27
    • 19
    • 17
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 27
    Lapin
    Clonalité
    • 27
    Polyclonal
    Conjugué
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp INTS3 est non-conjugé
    Application
    • 23
    • 13
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    integrator complex subunit 3
    Isotype
    IgG
    Top Product
    Discover our top product INTS3 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IP: 1:200-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    INTS3 (Integrator Complex Subunit 3 (INTS3))
    Autre désignation
    INTS3 (INTS3 Produits)
    Sujet
    Synonyms:C1orf193, C1orf60 Background:Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs(snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain(CTD) of RNA polymerase II largest subunit(POLR2A) and is recruited to the U1 and U2 snRNAs genes. Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks(DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.
    Poids moléculaire
    118kd
    ID gène
    65123
    UniProt
    Q68E01
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