IFIT2 anticorps

N° du produit ABIN7115383

Détail du produit anti-IFIT2 anticorps

Antigène: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFIT2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: interferon-induced protein with tetratricopeptide repeats 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:1000, IHC: 1:50-1:500, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur IFIT2

Antigène: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Autre désignation: IFIT2 (IFIT2 Produits)

Synonymes: anticorps G10P2, anticorps GARG-39, anticorps IFI-54, anticorps IFI-54K, anticorps IFI54, anticorps IFIT-2, anticorps ISG-54 K, anticorps ISG-54K, anticorps ISG54, anticorps P54, anticorps cig42, anticorps wu:fb58d07, anticorps DKFZp468G198, anticorps AV302338, anticorps Ifi54, anticorps interferon induced protein with tetratricopeptide repeats 2, anticorps interferon-induced protein with tetratricopeptide repeats 2, anticorps interferon-induced protein with tetratricopeptide repeats 15, anticorps IFIT2, anticorps Ifit2, anticorps ifit15

Sujet: Synonyms:cig42, G10P2, GARG 39, IFI 54, IFI 54K, IFI54, IFIT 2, IFIT2, ISG 54 K, ISG 54K, ISG54 Background:IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.

Poids moléculaire: 50-55 kDa

ID gène: 3433

UniProt: P09913