IL-6 Receptor anticorps

N° du produit ABIN7115473

Détail du produit anti-IL-6 Receptor anticorps

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-6 Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: interleukin 6 receptor

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:1000, IHC: 1:50-1:200, IP: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur IL-6 Receptor

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Autre désignation: IL6R (IL6R Produits)

Synonymes: anticorps IL6R, anticorps il-6ra, anticorps CD126, anticorps IL-6R-1, anticorps IL-6RA, anticorps IL6Q, anticorps IL6RA, anticorps IL6RQ, anticorps gp80, anticorps IL6R1, anticorps Il6ra, anticorps IL-6Ralpha, anticorps IL-6R, anticorps Il6r, anticorps interleukin 6 receptor, anticorps interleukin 6 receptor, alpha, anticorps IL6R, anticorps il6r, anticorps Il6r, anticorps Il6ra

Sujet: Synonyms:CD126, gp80, IL 6 receptor subunit alpha, IL 6R 1, IL 6R alpha, IL 6R subunit alpha, IL 6RA, IL-6 R alpha, IL-6R, IL6RA, interleukin 6 receptor, Membrane glycoprotein 80 Background:Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.

Poids moléculaire: 80 kDa

ID gène: 3570

UniProt: P08887

Pathways: Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints