Inversin anticorps

N° du produit ABIN7115502

Détail du produit anti-Inversin anticorps

Antigène: Inversin (INVS)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Inversin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: inversin

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Inversin

Antigène: Inversin (INVS)

Autre désignation: INVS (INVS Produits)

Synonymes: anticorps invs-a, anticorps INVS, anticorps MGC140477, anticorps inv, anticorps NPH2, anticorps NPHP2, anticorps INV, anticorps Nphp2, anticorps RGD1563359, anticorps wu:fe47e11, anticorps inversin S homeolog, anticorps inversin, anticorps Inversin, anticorps invs.S, anticorps INVS, anticorps Bm1_38710, anticorps PTRG_09181, anticorps EAMY_RS33690, anticorps LOAG_11716, anticorps invs, anticorps Invs

Sujet: Synonyms:INV, NPHP2 Background:Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled(DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8(By similarity). Does not seem to be strictly required for ciliogenesis(By similarity).

Poids moléculaire: 110-115 kDa

ID gène: 27130

UniProt: Q9Y283