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Inversin anticorps

INVS Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7115502
  • Antigène Voir toutes Inversin (INVS) Anticorps
    Inversin (INVS)
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 21
    • 1
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Inversin est non-conjugé
    Application
    • 18
    • 13
    • 13
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    inversin
    Isotype
    IgG
    Top Product
    Discover our top product INVS Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    Inversin (INVS)
    Autre désignation
    INVS (INVS Produits)
    Synonymes
    anticorps invs-a, anticorps INVS, anticorps MGC140477, anticorps inv, anticorps NPH2, anticorps NPHP2, anticorps INV, anticorps Nphp2, anticorps RGD1563359, anticorps wu:fe47e11, anticorps inversin S homeolog, anticorps inversin, anticorps Inversin, anticorps invs.S, anticorps INVS, anticorps Bm1_38710, anticorps PTRG_09181, anticorps EAMY_RS33690, anticorps LOAG_11716, anticorps invs, anticorps Invs
    Sujet
    Synonyms:INV, NPHP2 Background:Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled(DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8(By similarity). Does not seem to be strictly required for ciliogenesis(By similarity).
    Poids moléculaire
    110-115 kDa
    ID gène
    27130
    UniProt
    Q9Y283
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