anticorps zgc:76933, anticorps 1810045K06Rik, anticorps D330008A20, anticorps mKIAA0469, anticorps RGD1305863, anticorps kelch-like family member 21, anticorps kelch like family member 21, anticorps kelch like family member 21 L homeolog, anticorps kelch-like 21, anticorps klhl21, anticorps KLHL21, anticorps klhl21.L, anticorps Klhl21
Sujet
Synonyms:KIAA0469 Background:Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex(CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.