KLHL22 anticorps
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- Antigène Voir toutes KLHL22 Anticorps
- KLHL22 (Kelch-Like 22 (KLHL22))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KLHL22 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- kelch-like 22(Drosophila)
- Isotype
- IgG
- Top Product
- Discover our top product KLHL22 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- KLHL22 (Kelch-Like 22 (KLHL22))
- Autre désignation
- KLHL22 (KLHL22 Produits)
- Synonymes
- anticorps 2610318I18Rik, anticorps Kelchl, anticorps KELCHL, anticorps RGD1306288, anticorps kelch-like 22, anticorps kelch like family member 22, anticorps kelch-like family member 22, anticorps Klhl22, anticorps KLHL22
- Sujet
- Synonyms: Background:Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint(SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
- Poids moléculaire
- 72 kDa
- ID gène
- 84861
- UniProt
- Q53GT1
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