anticorps RGD1306683, anticorps wu:fb92d03, anticorps wu:fd15e07, anticorps 3110040D16RIK, anticorps MGC98945, anticorps LARP, anticorps 1810024J12Rik, anticorps 3110040D16Rik, anticorps Larp, anticorps mKIAA0731, anticorps La ribonucleoprotein domain family, member 1, anticorps La ribonucleoprotein domain family member 1, anticorps La ribonucleoprotein domain family member 1 L homeolog, anticorps Larp1, anticorps larp1, anticorps LARP1, anticorps larp1.L
Sujet
Synonyms:KIAA0731, LARP Background:RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine(5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation. Positively regulates the replication of dengue virus(DENV)(PubMed:26735137).