LRP5 anticorps

N° du produit ABIN7115919

Détail du produit anti-LRP5 anticorps

Antigène: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRP5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: low density lipoprotein receptor-related protein 5

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur LRP5

Antigène: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Autre désignation: LRP5 (LRP5 Produits)

Synonymes: anticorps Xlrp5, anticorps bmnd1, anticorps evr1, anticorps evr4, anticorps hbm, anticorps lr3, anticorps lrp5-A, anticorps lrp7, anticorps oppg, anticorps ops, anticorps opta1, anticorps vbch2, anticorps LRP5, anticorps LRP6, anticorps BMND1, anticorps EVR1, anticorps EVR4, anticorps HBM, anticorps LR3, anticorps LRP7, anticorps OPPG, anticorps OPS, anticorps OPTA1, anticorps VBCH2, anticorps mKIAA4142, anticorps low-density lipoprotein receptor-related protein 5, anticorps LDL receptor related protein 5, anticorps LDL receptor related protein 5 L homeolog, anticorps low density lipoprotein receptor-related protein 5, anticorps LDL receptor related protein 5 like, anticorps LOC100147353, anticorps LRP5, anticorps lrp5.L, anticorps lrp5, anticorps Lrp5, anticorps LRP5L

Sujet: Synonyms:LR3, LRP7 Background:This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 150 kDa

ID gène: 4041

UniProt: O75197

Pathways: Signalisation WNT, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation