anticorps Mage-a6, anticorps CT1.6, anticorps MAGE-3b, anticorps MAGE3B, anticorps MAGE6, anticorps melanoma antigen, family A, 6, anticorps MAGE family member A6, anticorps Magea6, anticorps MAGEA6
Sujet
Synonyms:MAGE6 Background:Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.