anticorps Rkhd2, anticorps RKHD2, anticorps rkhd2, anticorps bm-013, anticorps rnf194, anticorps MEX-3C, anticorps RNF194, anticorps A130001D14Rik, anticorps BC035207, anticorps BM-013, anticorps mex-3 RNA binding family member C, anticorps mex3 RNA binding family member C, anticorps Mex3c, anticorps MEX3C, anticorps mex3c
Sujet
Synonyms:RKHD2, RNF194 Background:E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.