MICAL2 anticorps

N° du produit ABIN7116286

Détail du produit anti-MICAL2 anticorps

Antigène: MICAL2 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MICAL2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: microtubule associated monoxygenase, calponin and LIM domain containing 2

Isotype: IgG

Information d'application

Indications d'application: IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur MICAL2

Antigène: MICAL2 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2))

Autre désignation: MICAL2 (MICAL2 Produits)

Synonymes: anticorps MICAL-2, anticorps MICAL2PV1, anticorps MICAL2PV2, anticorps 5330438E18Rik, anticorps 9530064J02, anticorps mKIAA0750, anticorps RGD1311773, anticorps microtubule associated monooxygenase, calponin and LIM domain containing 2, anticorps MICAL2, anticorps Mical2

Sujet: Synonyms:KIAA0750, MICAL2PV1, MICAL2PV2 Background:Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.

Poids moléculaire: 95, 112 kDa

ID gène: 9645

UniProt: O94851