MACF1 anticorps

N° du produit ABIN7116291

Détail du produit anti-MACF1 anticorps

Antigène: MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MACF1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: microtubule-actin crosslinking factor 1

Isotype: IgG

Information d'application

Indications d'application: IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur MACF1

Antigène: MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))

Autre désignation: MACF1 (MACF1 Produits)

Synonymes: anticorps ABP620, anticorps ACF7, anticorps MACF, anticorps OFC4, anticorps Acf7, anticorps Aclp7, anticorps R74989, anticorps mKIAA0465, anticorps MACF1, anticorps fc46g01, anticorps wu:fc46g01, anticorps si:rp71-45k5.7, anticorps acf7, anticorps macf, anticorps ofc4, anticorps abp620, anticorps DKFZp469K2016, anticorps Kiaa0754, anticorps mKIAA0754, anticorps microtubule-actin crosslinking factor 1, anticorps microtubule-actin crosslinking factor 1a, anticorps microtubule-actin cross-linking factor 1, anticorps dual specificity protein kinase CLK3, anticorps microtubule-actin cross-linking factor 1, isoforms 1/2/3/5, anticorps KIAA0754, anticorps RIKEN cDNA D830031N03 gene, anticorps MACF1, anticorps Macf1, anticorps macf1a, anticorps macf1, anticorps LOC100175356, anticorps LOC100514848, anticorps LOC100550622, anticorps KIAA0754, anticorps D830031N03Rik

Sujet: Synonyms:ABP620, ACF7, KIAA0465, KIAA1251 Background:Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex(composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions(FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells(By similarity).

Poids moléculaire: 83 kDa

ID gène: 23499

UniProt: Q9UPN3