MAPKBP1 anticorps

N° du produit ABIN7116438

Détail du produit anti-MAPKBP1 anticorps

Antigène: MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKBP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: mitogen-activated protein kinase binding protein 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200 - 1:500, IHC: 1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur MAPKBP1

Antigène: MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))

Autre désignation: MAPKBP1 (MAPKBP1 Produits)

Synonymes: anticorps MGC83682, anticorps JNKBP-1, anticorps 2810483F24Rik, anticorps AW123212, anticorps Jnkbp1, anticorps mKIAA0596, anticorps mitogen-activated protein kinase binding protein 1 L homeolog, anticorps mitogen-activated protein kinase binding protein 1, anticorps mitogen activated protein kinase binding protein 1, anticorps mapkbp1.L, anticorps MAPKBP1, anticorps Mapkbp1

Sujet: Synonyms:JNKBP1, KIAA0596 Background:MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1, 514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Poids moléculaire: 165 kDa

ID gène: 23005

UniProt: O60336